Primobolan Depot: A Complete Review on the Benefits and Side Effects of This Popular Steroid

Primobolan Depot: A Complete Review on the Benefits and Side Effects of This Popular Steroid

What is Primobolan Depot?

Primobolan Depot is a steroid with the chemical name methenolone enanthate. It is used to increase muscle mass and strength. It is an oral and injectable version of methenolone that is used in the treatment of anemia, muscle wasting illnesses, osteoporosis, and as a component of male hormone replacement therapy.

Primobolan Depot is an injectable that is administered once or twice each week. Because of the drug’s short half-life, it may be given on a daily or every other day basis, but not more often than that.

If there are significant muscles in the buttocks or thigh region, injections should be delivered deep into the muscle mass to prevent harm to any blood arteries.

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What are the benefits of Primobolan Depot?

Primobolan Depot benefits

Primobolan Depot is an anabolic steroid that is used to increase muscle mass. It is one of the most widely used injectable anabolic steroids in the world, and it is also one of the most expensive.

Primobolan Depot is popular among bodybuilders and sportsmen since it has few negative effects and does not interfere with the body’s natural testosterone production in any significant way. This product also has no estrogenic effects, which indicates that it may be taken by males who are sensitive to these types of adverse effects.

The half-life of Primobolan Depot is likewise quite short; as a result, its effects are only visible for around two days following injection. This makes it simpler for bodybuilders to keep up with their cycle schedules since they must inject themselves with this substance on a daily basis in order to retain the desired results.

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Why do athletes and bodybuilders take Primobolan?

For starters, it is one of the few anabolic steroids available on the market that is suitable for female use. Primobolan, like Anavar, has a very low virilization rating, which means that women may take it without having to worry about acquiring facial hair, baldness, or a deeper voice – which is fantastic!

Two, there is the whole historical background to Arnold Schwarzenegger’s use of Primobolan during his Mr. Olympia days. Arnie’s famed body, despite the fact that it has never been definitively proven, has increased demand for this steroid, since, let us face it, we all want to look like Arnie.

All of the above, however, is just scratching the surface…

One of the numerous reasons why sportsmen and bodybuilders take Primobolan (particularly Primobolan depot) is because it provides the following benefits:

Given that this DHT-based anabolic steroid has not been 17-alpha-alkylated but rather 1-methylated (for oral bioavailability), it may be taken between cycles – during ‘off time’ – to assist in the preservation of muscle growth and strength gains. As a matter of fact, it is ideal for reducing cycles since it may prevent muscle loss and instead aid you to preserve all of the muscle you developed during your bulking phase while still enabling you to get the benefits of a calorie-restricted eating plan. Primobolan can offer excellent conditioning benefits when combined with a well-planned diet, which will leave you appearing tougher, more defined, and chiseled as a result.

It has a potency that is just somewhat lower than Deca Durabolin, though.

When considering anabolic effects, it produces less inhibition than testosterone or Deca Durabolin (since it does not convert into DHT), has lower central nervous system activity, and has a lower chance of aromatization (which may result in man boobs, which is not something I am interested in).

Due to the fact that it is a moderate anabolic steroid, it will not convert into estrogen or cause breast growth in males.

Active and total testosterone levels are raised via the promotion of sex hormone-binding globulin (SHBG) and luteinizing hormone (LH) (LH).

It has little to no adverse effects when compared to other top anabolic steroids, which are known to induce liver poisoning and damage, bigger breasts, shrinking testicles, or a higher voice, as well as mood swings and roid fury (and other symptoms). Instead, you may prevent all of these problems by using PCT and carefully monitoring your doses.

You may expect its performance-enhancing benefits to persist for many months – so your hard work will not be vaporized in a puff of smoke. Primobolan, on the other hand, will preserve your lean muscle tissues from breakdown, will promote enhanced fat burning, and will assist you in maintaining your muscular gains long after you have stopped using it.

Its ability to increase strength without increasing muscle mass – Primobolan has the ability to increase strength without increasing muscular mass, which is beneficial for athletes who are not bodybuilders.

It aids in the improvement of muscle repair as well as endurance.

It is an effective fat burner since it aids in increasing your metabolic rate.

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The advantages of using Primobolan

1. Primobolan Acetate is a steroid that is taken orally. Primobolan Depot is the injectable version of the drug.

The majority of steroid users prefer to toss the name Primo about without really mentioning the version of the steroid they are currently utilizing in their conversation.

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Primobolan is available in two different forms.

There is also Primobolan Acetate, which is the steroid’s oral form, which is available. This is due to the fact that acetate is a short-acting ester and that oral Primo has a very short half-life, which means that you would have to take this on a daily basis.

In addition to that, there is Primobolan Depot, which is an injectable form of the drug. It is the same Methenolone hormone that was used in the previous experiment. However, it is accompanied by the long-acting enanthate ester, which allows you to get away with two or three pins every week at the most.

The Depot version seems to provide somewhat better outcomes than the other versions. However, this is based only on anecdotal evidence.

Primo is one of the steroids that are well-known for causing Post Injection Pain, and we must admit that it is one of the most painful. So, unless you have a strong preference for injectable steroids solely, we recommend opting for the oral form.

See info about Primobolan advantages

2. It is a very safe anabolic steroid.

We do not often associate the words “safe” and “steroids” with one another. That is a bit of a conundrum.

Primobolan, on the other hand, is one of the compounds where we tend to disagree a bit. It has been used to treat preterm infants1, among other things. If it is not safe, we are not sure what is either.

You can basically run grams of this stuff for months on end without seeing even the tiniest performance degradation in your system.

There are, however, certain caveats to consider.

First and foremost, you must be able to pay for Primo. Because of the high cost of running grams, you need a budget close to $100-150 every week to keep up with the Joneses. In exchange for this, the profits that you get from it are somewhat little.

Second, you must have access to a reputable supplier that can provide you with genuine Primo. Believe us when we say that this is true. Primo is a very difficult anabolic steroid to get in large quantities. At the very least, the legitimate stuff is. The majority of what is marketed as Primo on the market is really Masteron that has been underdosed.

3. Primo will make you drier, more vascular, and more powerful.

A lot of people are baffled by the obsession that bodybuilders have with Primo Levi’s and its products.

Particularly since the consequences that it generates are so modest that the majority of people will not even recognize that they have changed in any way with their bodies.

In contrast, Primobolan, which derives from the hormone DHT, has a very significant affinity for attaching to androgen receptors, and so indirectly stimulates lipolysis. Because of this, there have been similarities drawn between Trenbolone and Masteron.

Even if you are not strictly adhering to a diet plan, you will still maintain a healthy weight while taking Primo.

Along with fat reduction, it also has the added benefit of increased vascularity. All of the gains you acquire while on a Primo cycle will be dry and vascular in nature.

Prepare yourself for modest strength increases as well. Primobolan will help you break past any plateaus you may be experiencing in your workouts.

4. It is a fantastic cutting compound

One of the most helpful characteristics of Primo is that it considerably enhances nitrogen retention, which in turn helps to avoid a catabolic condition from occurring.

As a result, it is one of the most effective substances to use throughout a cutting cycle.

Another benefit is that it has a beneficial impact on your immune system, which is always a plus when you are dealing with a severe cut.

5. It is very effective when used with the majority of other steroids.

Using Primobolan in conjunction with Testosterone can discreetly enhance the outcomes of your Testosterone cycle without you even realizing that you are taking an extra substance.

Primo does not include 17CAA, which means that it will not put as much strain on your liver as other orals do. It has no aromatizing properties. Moreover, it does not have any significant androgenic adverse effects.

Women athletes may run it for lengthy periods of time with minimal chance of being virilized.

Despite this, it will have a subtle positive impact on the outcomes of your test cycle.

The anti-estrogenic properties of this supplement will aid in the reduction of Testosterone aromatization. One of the reasons why a large number of guys on TRT choose to include Primo on their trip. Making E2 management a breeze, and adding that wonderful, extra kick to their gym time is something that nobody can complain about!

The fat reduction is beneficial, as is the increase in vascularity, since Test is a rather moist substance, or may be for a lot of individuals.

Primo is also a fantastic partner for Deca, as you can see here.

6. Do not fear high dosages

Do not compare the dosages of Primo with those of any other substance. Primo is only effective if it is used in huge quantities, which means it must be used in enormous numbers. The majority of individuals take 600-900mg of the chemical daily. Serious sportsmen and bodybuilders, on the other hand, will not mind consuming grams of the substance.

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In a vintage book on steroid usage from the 1970s and 1980s, it was said that any athlete who had access to Pharma grade Primo would run doses in excess of 1-2 grams for at least 16-20 weeks throughout their cycles.

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How does Primobolan work?

How does Primobolan work

Methenolone is a derivative of DHT (or, to be more exact, it is a structurally changed version of DHT), and it has a number of biological effects. It has an additional double bond between carbon one and carbon two, which contributes to the anabolic characteristic of this hormone being enhanced. It also has an extra 1-methyl group, which helps to keep it from being broken down by the liver. The inclusion of the acetate ester provides further protection against hepatic metabolism.

Its oral form is highly advantageous since it is the only oral steroid that is not a C17-aa steroid, which makes it very effective. As a result of the absence of C17-aa, it is regarded mild/weak when compared to other anabolic steroids, which indicates that most men would not experience the same amount of anabolic activity as they would with other testosterone derivatives.

That is why many men choose to use Primobolan Depot – since the injection is more potent – while most women prefer to use the oral version, which has the same moderate side effects as the injectable type.

Primobolan functions in a similar fashion to other anabolic steroids in many aspects. To a certain extent, it promotes protein synthesis while also causing a little rise in your red blood cell count.

It does, however, possess three unique characteristics that set it apart from the competition:

As a result, it significantly enhances nitrogen retention, preventing catabolic states from occurring and allowing you to effectively create lean muscle tissue. True, these benefits will not be significant, but they will be significant nevertheless.

It has a high affinity for androgen receptors, and this has been connected to the induction of direct lipolysis in animals. While all anabolic steroids have the potential to enhance your metabolic rate, Primobolan is considered to specifically aid in fat reduction, making it an excellent choice for reducing.

According to research, it has the potential to greatly improve your immune system. In fact, it has been used effectively in the treatment of AIDS, providing people with an immune boost as well as protection against muscle loss.

Dosage and cycle information for Primobolan

Primobolan dosage for males is about 200-400mg per week, or 50-150mg per day (if you are competing), depending on their height and weight. Women need just 50-100mg per week, which is far less than males (although some studies suggest 25-75mgs per day is safe).



When used in conjunction with Deca Durabolin, Testosterone, Trenbolone, Masteron, Anavar, Winstrol, Dianabol, Clenbuterol, T3, or Anadrol, it produces the finest results.

It is recommended that you use Nolvadex, HCG, or Clomid towards the end or immediately after the end of your cycle, as this helps to increase the bioavailability of any other steroids you have used during your cycle, while also preventing any estrogenic side effects such as oily skin, acne, bloating, or gynecomastia.

Primobolan is often taken by athletes between cycles – during their ‘off-time’ – because of its reputation as a potent fat burner. This allows athletes to preserve their muscle mass and whatever strength improvements they have gained throughout their training. A Primobolan cycle for pre-contest trimming is not uncommon among competitive bodybuilders, and it is recommended by the American Bodybuilding Association.

The typical Primobolan cycle is as follows:

Primo is often taken as part of an 8-week cycle, regardless of how much you take – from the low 50mg a day to the competitive 100mg – and how often you take it. Take note of how we used the phrase ‘part of the cycle’ here. This is due to the fact that the entire duration of Primo’s usage should not exceed 6 weeks. As a consequence, many sportsmen will divide their anabolic steroid cycles and will utilize numerous anabolic steroids at the same time. For example, males often begin with Sustanon 250 and Anadrol for the first two weeks, then Sustanon 250, Anadrol, and Nolvadex from weeks 2-4, then moving to Sustanon 250, Primobolan, and Nolvadex from weeks 5-8, and finally concluding with just Nolvadex for the last two weeks.

It is important to note that for individuals who are taking Primo for the first time, your Primobolan cycle will only consist of 25mg each day.

Although women are capable of handling a 25-50mg dosage of Primobolan per day, it is advised that they take lesser doses of Primobolan and combine it with Anavar in order to maximize their results.

Risks and side effects of using Primobolan

Primobolan risks and side effects

Primobolan is a gentler anabolic steroid than other anabolic steroids and promises safer benefits; but, abuse of the drug, like with any other substance, may result in some very unpleasant adverse effects. In spite of the fact that there have not been many scientific studies conducted on the substance (apart from those conducted on rats), persons who have taken the steroid have experienced several negative side effects.

Some of the most common Primobolan adverse effects include depression, acne, oily skin, hair loss/balding, excess body hair, increases in poor cholesterol, and gynecomastia (male breast growth) (this usually only occurs if it has been stacked with another anabolic steroid).

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If you stick to safe, lower doses of medication, the likelihood of experiencing these side effects should be reduced to an absolute minimum. If you have sensitive skin, for example, we recommend that you err on the side of caution, particularly if you are already inclined to them.

Women, in particular, should exercise caution.

Yes, it is regarded to be one of the safest anabolic steroids for women; nevertheless, it is not fully immune from the risk of virilization when used in conjunction with testosterone. In the event that you deviate from the suggested dose, you may have increased body hair, a deeper voice, menstrual cycle difficulties, and baldness (note: these side effects will disappear rapidly if you discontinue using it).

Also not suggested are those who have been diagnosed with testicular atrophy, testicular cancer, testicular cancer, prostate cancer, breast cancer, liver damage, renal damage (including kidney failure), stroke, high blood pressure, or respiratory issues.

Similarly, if you have taken any of the following medications: Prasterone, Tamoxifen, DHEA, or Androstenedione, you should proceed with caution, since it may cause aromatization.

It is critical that we bring up the topic of testosterone suppression at this point in the discussion. Primobolan is not immune to this effect and will, to a certain extent, reduce natural testosterone production. It is true that the risk is lower than that of other anabolic steroids; nonetheless, it will occur unless you include PCT/exogenous treatment in your cycle to guarantee a rapid recovery from your cycle.

Other considerations are as follows:

Never take more than one dosage at a time, even if you have missed a dose. Simply skip it and continue with your next appointment at the specified time and dosage. Particularly important is the fact that you have fewer than 6 hours until your next Primobolan dose.

Oral Primobolan is not considered a hepatotoxic steroid since there is no evidence that it will induce liver stress when administered orally. The usage of Primobolan, on the other hand, has been linked to the death of an old man who suffered from liver toxicity, failure, and death as a result of his use. This is significant, however. True, this is the first time this has happened in 50 years, but the fact that it has happened indicates that you should exercise caution in the future.

Primobolan, on the other hand, does not aromatize and does not promote water retention since it does not contain any progestins. Besides that, since it does not create excessive water retention, it will not cause any problems with blood pressure.

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User reviews

Personal review from Redditor YappaBanga

I’ve been on this subreddit for some time and have found it to be an incredible resource. I will take today to try and give back by sharing what my first-hand experience of 2 years on Primo has been like. The constant claims of Primo being faked in my opinion are overblown. The raw compound is far less rare and expensive than this sub seems to believe.

Here are my key takeaways from running Primo at various dosages for the past 24 months.

  1. Primo WILL lower your estradiol levels similarly to EQ. In order to properly run Primo, you should dose your test a bit higher in order to offset the AI effect of Primo. Lately, I’ve come to believe this is also the function of why many golden-era bodybuilders seemed not to have estrogen sides when running high doses of Dbol/Test without an AI. I would go as far to say legitimate Primo mixed with high test/DBol is probably what allowed these guys to build the physiques they achieved. (Lab 1) (Lab 2) (Lab 3).
  2. Primo will have ZERO effect on lipids, kidney and liver function. It literally is THE safest steroid in my opinion. A fool proof method of seeing if you received fake Primo is to check if you have any impacts to your lipid profile. For me, Mast kills my libido and greatly effects my lipid profile. I ran Mast recently and saw a significant impacts to my lipid profile shown here (Lab 4). Versus months of running it prior with almost perfect lipids shown above.
  3. Primo can be run in lower dosages (200mg – 500mg) but really has a fantastic effect when bumped up past 600+ mg a week. I’m 6’7 (200cm) around 245lbs (11kg) so I find that I typically have to run higher dosages of everything, but your situation may be different. This is what made the Mast effect on my lipid panel so pronounced.
  4. Combined with 6iu of HGH EOD and I can’t imagine why anyone would run anything else. You can get big on Primo, yes it needs to be dosed high but if you’re a nut like me and pin ED anyway, it should be a staple for everyone. I recently ran tren (dosed high) and in my experience, this is the only other compound that provided me a different look/feel that I couldn’t achieve with varied levels of Primo.
  5. I have not experienced a single side (besides low E2) from Primo independently. Libido is unchanged, mental state is not impacted, and my daily 5K time gets better every month. If you’re looking for the ultimate compound for physique/well being and overall performance, its Primo.

Obviously my experience is anecdotal, I’m far from an expert on human biology but I do get bloods every month. Feel free to reach out if you’re curious about my experience.